Browsing by Author "Cassorla Goluboff, Fernando"

Now showing items 1-20 of 33

    • Anti-Mullerian hormone levels in peripubertal daughters of women with polycystic ovary syndrome 
      Crisosto King, Nicolás; Codner Dujovne, Ethel; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Sánchez, Fernando; Cassorla Goluboff, Fernando; Sir Petermann, Lidia (ENDOCRINE SOC, 2007-07)
      Context: We have previously observed increased anti-Mullerian hormone (AMH) levels in prepubertal daughters of polycystic ovary syndrome (PCOS) women, suggesting that these girls may have an altered follicular development. ...
    • C-Reactive protein and insulin growth factor 1 serum levels during the menstrual cycle in adolescents with ... 
      Codner Dujovne, Ethel; Merino, P. M.; Martínez, D.; Lopez, P.; Godoy, C.; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando; Pérez Bravo, Francisco (Blackwell Publishing Ltd, 2016)
      © 2016 Diabetes UK.Aims: To evaluate C-reactive protein, insulin growth factor 1 and lipid levels during the follicular and luteal phases in adolescents with Type 1 diabetes. Methods: Adolescents with Type 1 diabetes (N = ...
    • Clinical and molecular characterization of Chilean patients with Léri-Weill dyschondrosteosis 
      Rodríguez, Fernando Adrián; Unanue Morales, Nancy; Hernández Cárdenas, María Isabel; Basaure, Javiera; Heath, Karen Elise; Cassorla Goluboff, Fernando (2013)
      Aim: L é ri-Weill dyschondrosteosis (LWD) is a mesomelic dysplasia with disproportionate short stature associated with short stature homeobox-containing gene (SHOX) haploinsufficiency. The objective of this study was ...
    • Cronología del desarrollo puberal en niñas escolares de Santiago: relación con nivel socio-económico e ... 
      Codner Dujovne, Ethel; Unanue Morales, Nancy; Gaete Vásquez, Ximena; Barrera P., Alvaro; Mook-Kanamori, Dennis; Bazaes Castillo, Rodrigo Antonio; Avila A., Alejandra; Cassorla Goluboff, Fernando (2004)
      Background: Recent studies in the United States have demonstrated that a significant proportion of girls show thelarche before the age of eight years. Nutritional status, geographic influences and racial factors are known ...
    • Diagnostic criteria for polycystic ovary syndrome and ovarian morphology in women with type 1 diabetes mellitus 
      Codner Dujovne, Ethel; Soto, Néstor; López, Patricia; Trejo, León; Avila, Alejandra; Eyzaguirre, Francisca C.; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (ENDOCRINE SOC, 2006-06)
      Context: The criteria for diagnosis of polycystic ovary syndrome (PCOS) have been modified and now include polycystic ovary morphology (PCOM). Objective: The purpose of this study was to determine the frequency of PCOS ...
    • Differential effect of two hormonal contraceptives on the relative telomere length of youth with type 1 ... 
      Castro Gálvez, María Andrea; Lardone, María Cecilia; Giraudo Abarca, Franco; López Cuevas, Patricia; Ortiz, Eliana; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (Oxford, 2024)
    • Edad de la menarquia y su relación con el nivel socioeconómico e índice de masa corporal 
      Hernández, María Isabel; Unanue Morales, Nancy; Gaete, Ximena; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (SOC MEDICA SANTIAGO, 2007-11)
      Background: A decline in the age of menarche was observed from early 1900s to the 1970s. However, it is not known if a further decline ocurred thereafter. Aim: To evaluate the age of menarche in girls from Santiago, Chile ...
    • Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: ... 
      Leschek, Ellen Werber; Rose, Susan R.; Yanovski, Jack A.; Conley, Mary; Quigley, Charmian A.; Chipman, John J.; Crowe, Brenda J.; Ross, Judith L.; Cassorla Goluboff, Fernando; Blum, Werner F.; Cutler, Gordon B.; Baron, Jeffrey (2004)
      GH is often used to treat children with idiopathic short stature despite the lack of definitive, long-term studies of efficacy. We performed a randomized, double-blind, placebo-controlled trial to determine the effect of ...
    • Effects of levothyroxine on growth hormone (gh) sensitivity in children with idiopathic short stature 
      García, Roberto J.; Iñíguez Vila, Germán; Gaete, Ximena; Linares, Jeanette; Ocaranza Osses, Paula; Ávila, Alejandra; Román, Rossana; Cassorla Goluboff, Fernando (Elsevier, 2014)
      Background: The possible relationship between the circulating concentrations of T4 and GH sensitivity has not been elucidated. Objective: The aim of this study is to evaluate the effect of levothyroxine supplementation ...
    • Effects of Prenatal Ethanol Exposure on Postnatal Growth and the Insulin-Like Growth Factor Axis 
      Aros Aránguiz, Sofía Daniela; Mills, James L.; Iñíguez Vila, Germán; Ávila, Alejandra; Conley, Mary R.; Troendle, James; Cox, Christopher; Cassorla Goluboff, Fernando (KARGER, 2011)
      Aims:To study the effect of in-utero alcohol exposure on the insulin-like growth factor axis (IGF) and leptin during infancy and childhood, considering that exposed children may exhibit pre- and postnatal growth retardation. ...
    • Effects of the IGF-I/IGFBP-3 complex on GH and ghrelin nocturnal concentrations in low birth weight children 
      Iñíguez Vila, Germán; Salazar, Teresa; Román, Rossana; Avila, Alejandra; Gunnt, Ronald D.; Cassorla Goluboff, Fernando (BLACKWELL, 2006-11)
      Objective There is limited information regarding the effects of IGF-I and/or IGFBP-3 on circulating ghrelin concentrations. To determine the effects of IGF-I on GH and ghrelin concentrations, we examined the GH and ghrelin ...
    • Effects of thyroid hormone on the GH signal transduction pathway 
      Ocaranza Osses, Paula; Lammoglia, Juan Javier; Iñíguez Vila, Germán; Román, Rossana; Cassorla Goluboff, Fernando (Elsevier, 2014)
      Background/aim: The importance of thyroid hormone on growth and development in children iswell recognized. In addition, linear growth is highly dependent on the response of peripheral tissues to growth hormone, a ...
    • Eye Malformations in Children with Heavy Alcohol Exposure in Utero 
      Flanigan, Elizabeth Y.; Aros Aránguiz, Sofía Daniela; Ferraz Bueno, María Isabel; Conley, Mary; Troendle, James F.; Cassorla Goluboff, Fernando; Mills, James L. (2008-09)
      Objective To determine whether children who do not develop fetal alcohol syndrome (FAS) despite heavy alcohol exposure are at risk for eye abnormalities. Study design We screened 9628 pregnant women and identified 101 ...
    • Glucokinase mutations in young children with hyperglycemia 
      Codner Dujovne, Ethel; Deng, Liyong; Pérez Bravo, Francisco; Román, Rossana; Lanzano, Patricia; Cassorla Goluboff, Fernando; Chung, Wendy K. (JOHN WILEY & SONS, 2006-10)
      Background The etiology of mild hyperglycemia without ketoacidosis in young children is often unknown. Maturity onset diabetes of youth (MODY) is a form of diabetes mellitus (DM) characterized by fasting hyperglycernia ...
    • IGF-I sensitivity in small for gestational age children Sensibilidad a IGF-I en niños pequeños para la edad ... 
      Román R., Rossana; Iñíguez Vila, Germán; Salazar C., Teresa; Avila A., Alejandra; Barrera P., Alvaro; Fuentes G., Ariel; Mericq, Verónica; Gunn, Ronald D.; Cassorla Goluboff, Fernando (2006)
      Background: The lack of catch up growth (CUG) in small for gestational age (SGA) children may be related to a reduced sensitivity to insulin growth factor 1 (IGF-I). Aim: To assess the sensitivity to IGF-I in small for ...
    • IGF-IR signal transduction protein content and its activation by IGF-I in human placentas: relationship ... 
      Iñíguez Vila, Germán; Castro, Juan José; García Mora, Mirna; Kakarieka, Elena; Johnson Pena, María Cecilia; Cassorla Goluboff, Fernando; Mericq, Verónica (PLOS One, 2014)
      Introduction: The human placenta expresses the IGF-I and IGF-IR proteins and their intracellular signal components (IRS-1, AKT and mTOR). The aim of this study was to assess the IGF-IR content and activation of downstream ...
    • Increased growth velocity during prolonged ghrp-2 administration to growth hormone deficient children (GHD) 
      Merico, Maurizio; Cassorla Goluboff, Fernando; Salazar, G.; Avila, Alejandra; Iñíguez Vila, Germán; Bowers,; Mernam, (1997)
    • Klotho gene and protein in human placentas according to birth weight and gestational age 
      Iñíguez Vila, Germán; Gallardo, Pedro; Castro, Juan José; González, René; García, Mirna; Kakarieka, Elena; San Martín, Sebastián; Johnson, María Cecilia; Mericq, Verónica; Cassorla Goluboff, Fernando (Frontiers Media, 2019)
      Introduction: Fetal growth restriction may be the consequence of maternal, fetal, or placental factors. The insulin-like growth factors (IGFs) are major determinants of fetal growth, and are expressed in the mother, fetus ...
    • Low risk of impaired testicular sertoli and Leydig cell functions in boys with isolated hypospadias 
      Rey, Rodolfo A.; Codner Dujovne, Ethel; Iñíguez Vila, Germán; Bedecarrás, Patricia; Trigo, Romina; Okuma, Cecilia; Gottlieb, Silvia; Bergadá, Ignacio; Campo, Stella M.; Cassorla Goluboff, Fernando (ENDOCRINE SOC., 2005-11)
      Testicular dysfunction was observed in 57.1% and androgen end- organ defects in 7.2% of patients with hypospadias associated with cryptorchidism, micropenis, or ambiguous genitalia. In the remaining 35.7%, the disorder was ...
    • Markers of Oxidative Stress and Systemic Vasoconstriction in Pregnant Women Drinking ‡48 g of Alcohol per Day 
      Signore, Caroline; Aros Aránguiz, Sofía Daniela; Morrow, Jason D.; Troendle, James; Conley, Mary R.; Flanigan, Elizabeth Y.; Cassorla Goluboff, Fernando; Mills, James L. (BLACKWELL PUBLISHING, 2008-11)
      Background: The precise pathway by which alcohol causes the characteristic features of fetal alcohol spectrum disorders is unknown. Proposed mechanisms for fetal injury from maternal alcohol use include cellular damage ...